Description PROGRAM DESCRIPTIONThe NCI is implementing a program intended toconnect and closely coordi...
Description PROGRAM DESCRIPTIONThe NCI is implementing a program intended toconnect and closely coordinate the Division of Cancer Treatment and Diagnosis (DCTD s) immunotherapeutics and other drug development activities with thetranslational oriented clinical trials of the Center for Cancer Research s(CCR s) Comparative Oncology Program (COP), especially the treatment of dogswith natural occurring cancers that can inform the prioritization of DCTD sclinical trial portfolio and elucidate drug mechanisms of action that cannot bestudied readily in human patient populations. COP is launching a pilot program aimed to develop and oversee a seriesof comparative oncology Phase 0 studies, which assess novel anti-cancer agentsin naturally-occurring canine cancers. The pilot program will be undertaken incollaboration with the DCTD through the existing Comparative Oncology TrialsConsortium (COTC) infrastructure.KEYROLES/RESPONSIBILITIESThe Veterinary Oncologist will perform thefollowing tasks:Review, analyze and interpret laboratory animalpharmacology, toxicology and preclinical modelling/efficacy data provided bythe DCTDProvide protocol and SOP authorship inclusiveof literature review, including design of canine clinical trials with inputfrom COP leadership and toxicology, pharmacology, and assay development groupswithin the DCTDDemonstrate and maintain proficiency with theOracle C3D database for all data management tasks, but will also be responsiblefor maintenance of CCR Clinical Informatics Wiki sites and other applicableExcel spreadsheetsReview, analyze and interpret all data(clinical response, hematology, biochemistry, imaging, etc.) Generated in comparativecanine clinical trialsProvide monthly oral presentation of data via PowerPointslides to COP and DCTD leadershipBe responsible for direct, daily communicationswith COTC membership regarding protocol training and provision of protocolamendments, questions regarding canine patient management/adverse eventmanagementConduct monthly interviews via telephone withall canine clinical trial sites to verify entry and determine the attributionof all efficacy and toxicity data reported in C3DAuthor quarterly study reports, submitted tostudy sponsors and COP leadershipCo-author manuscripts that result from forcanine clinical trials, inclusive of manuscript writing, literature review,creation of figures/data tablesConduct laboratory studies to elucidate adeeper understanding of key questions that arise during these trialsQualifications BASIC QUALIFICATIONSTo be considered forthis position, you must minimally meet the knowledge, skills, and abilitieslisted below:Possession of a Doctor of Veterinary Medicine(DVM) or Veterinariae Medicinae Doctoris (VMD) degree from an AVMA (AmericanVeterinary Medical Association) accredited college or university according tothe Council for Higher Education Accreditation. Foreign degrees must beevaluated for U.S. equivalencyMust have completed a residency in an AmericanCollege of Veterinary Internal Medicine (ACVIM) or American College ofVeterinary Radiology (ACVR)-approved programIn addition to the educational requirements, aminimum of eight (8) years of experience including 3 years in veterinary oncologyor related fieldMust be able to obtain and maintain a securityclearanceExpected Competencies: Have specialized expertise: in canine cancersand their treatment; in the design, conduct and management of canine clinicaltrials; and in the conduct of translational laboratory experimentation Associated topics: ancmg, aoa, breast, cancer, hem onc, oncology, palliative, physician md, radiation, thedacare